(1) This product is used in combination with aminoglycosides or broad-spectrum penicillin, which has a synergistic effect.
(2) Heavy metal ions such as Ca2+, Mg2+, Fe3+ and Al3+ can chelate with this product and affect absorption.
(3) When combined with theophylline and caffeine, it can reduce the plasma protein binding rate, abnormally increase the concentration of theophylline and caffeine in the blood, and even cause symptoms of theophylline poisoning.
(4) This product has the effect of inhibiting liver drug enzymes, which can reduce the clearance rate of drugs mainly metabolized in the liver and increase the blood drug concentration.
(1) Degeneration of cartilage in young animals, affecting bone development and causing claudication and pain.
(2) Reactions of the digestive system include vomiting, loss of appetite, and diarrhea.
(3) Skin reactions include erythema, itching, urticaria and photosensitivity.
(4) Allergic reactions, ataxia, and seizures are occasionally seen in dogs and cats.